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Everything you need to know about glutamine and its benefits

Glutamine is a non-essential amino acid that plays a key role in many biological processes in the body. Although the body can synthesize it by itself, there are situations when its need exceeds production, especially during increased physical stress, intense exercise, or in periods of illness.

Glutamine is an essential amino acid with a wide range of health benefits. From supporting the immune system and gut health, through muscle recovery, to supporting brain function. This amino acid also plays a key role in maintaining overall health and performance. Supplementing with glutamine can be particularly beneficial for athletes, individuals under high physical or mental stress, and those who want to support their overall health. However, it is always important to consult any supplementation with an expert to ensure safety and effectiveness of use.


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Importance of glutamine for the human body

Glutamine is important for maintaining optimal immune system function. Immune system cells, such as lymphocytes and macrophages, use glutamine as an energy source. This amino acid also supports gut health by serving as fuel for enterocytes (intestinal lining cells), which is key to maintaining the integrity of the intestinal barrier and preventing pathogens from entering the bloodstream.

Another important function of glutamine is its role in muscle metabolism. During intense training, there is a loss of glutamine in the muscles, which can lead to catabolism (breakdown of muscle proteins). Supplementing with glutamine helps accelerate muscle recovery and reduce muscle fatigue.


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Health benefits of glutamine supplementation

Glutamine offers several health benefits that are supported by scientific research:

During periods of stress or intense physical activity, the immune system can be significantly weakened. Glutamine helps maintain immune cells in optimal condition, thereby increasing resistance to infections.

Maintaining a healthy intestinal barrier is key to overall health. Glutamine supports regeneration of the intestinal lining and improves nutrient absorption. For athletes and active individuals, muscle recovery is key. Glutamine helps to replenish muscle glycogen stores faster and shortens the time needed for recovery after strenuous training.

Glutamine plays a role in neutralizing ammonia, a toxic by-product of protein metabolism, which is important for maintaining optimal blood pH.

As a precursor of neurotransmitters glutamate and GABA (gamma-aminobutyric acid), glutamine contributes to regulating brain activity, mood and cognitive functions.

Maintaining proper levels of this key amino acid can lead to better physical performance, faster recovery, a stronger immune system, and overall better health. Remember, although glutamine is commonly available as a dietary supplement, it is always good to get professional advice before starting any new supplementation routine. Be informed, be healthy, and take advantage of all the benefits that glutamine can offer your body and mind.


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Recommended dosage and sources of glutamine

Recommended glutamine dosage can vary depending on individual needs and health status. Generally, it is recommended to start with a dose of 5-10 grams per day, divided into several doses. Athletes or people in periods of increased stress may need higher doses, up to 20-30 grams per day, but it is always advisable to consult supplementation with an expert.

Glutamine can be obtained from foods such as meat, fish, eggs, dairy products, spinach, and cabbage. However, to achieve optimal levels, it may be desirable to take glutamine in the form of dietary supplements, especially in active individuals or in periods of increased need.

Glutamine in the context of sports nutrition

For athletes, glutamine is an essential part of the supplementation plan. It increases cell hydration, which promotes protein synthesis and thus muscle growth. Studies have shown that supplementing with glutamine can reduce the rate of fatigue during long and intense workouts, thanks to its ability to improve nitrogen balance in the body.

In addition, glutamine increases the level of growth hormone, which is another benefit for athletes seeking to improve performance and recovery. Glutamine supplementation has also been shown to be effective in reducing muscle pain after exercise, which can enable athletes to train with higher intensity and frequency.


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Glutamine and mental health

Not only physical health, but also mental health can benefit from sufficient levels of glutamine. Glutamine is a precursor of glutamate, an excitatory neurotransmitter, which is key for cognitive functions, memory, and learning. In the body, glutamine also converts into GABA, an inhibitory neurotransmitter, which acts against anxiety and stress.

Studies suggest that glutamine supplementation can have a positive effect on mood and reduce anxiety. This effect is likely caused by its influence on the balance of neurotransmitters in the brain, which can contribute to better mental well-being and resistance to stress.


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Potential side effects and precautions

Although glutamine is generally considered safe, some people may experience side effects such as stomach discomfort, bloating, or diarrhea, especially at higher doses. It is important to start with lower doses and gradually increase them to allow the body to adapt.

People with certain health complications, such as liver or kidney problems, should consult the use of glutamine with a doctor to avoid potential complications.

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